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Needle-shaped Sensors Can Detect Multiple Sepsis Indicators
The device takes a pin prick of blood which is then put on the chip for the result to be read. Its needle shape means it could also be implanted and used on patients in intensive care.
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3D Protein Structure Aids Anti-cancer Drug Design
A research team has discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors. Their findings reveal a novel binding site that will promote drug design of more efficient E1 inhibitors.
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TB's Suicide System Could Be Its Undoing
TB holds a special toxin-antitoxin system with spectacular action: once the toxin is activated, all bacterial cells die, stopping the disease. Researchers are investigating how to turn the bacteria on itself.
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RNA Captured Interacting With Stress Granules
Individual RNA molecules have been captured interacting with stress granules, revealing how, when and where the RNAs move around – a process never before witnessed from start to finish.
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Novel Binding Site for Anti-cancer Drugs
A research team at the Medical University of South Carolina (MUSC) has discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors.
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"Good" Cholesterol Likened to "Velcro Ball"
Researchers report on an underappreciated part of high-density lipoprotein (HDL): not its lipids, but its proteins. They showed that a complex mix of genetic and environmental factors contribute to the protein makeup of HDL particles.
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Blood Gene Expression Markers Predictive of Pain
A breakthrough test to measure pain in patients could help stem the tide of the opioid crisis in Indiana, and throughout the rest of the nation.
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Animal Venoms Aid the Search for New Medicines
Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.
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Endocrine-disrupting Chemicals Linked to Equine Metabolic Syndrome
Endocrine-disrupting chemicals (EDCs) in a horse's environment may play a role in the development of equine metabolic syndrome (EMS).
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Measles Virus Vector Used to Streamline Cell Reprogramming
Using the measles virus vector; researchers have trimmed the multi-vector process with four reprogramming factors down to a single “one cycle” vector process.
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