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Akna is a key protein which regulates the differentiation of neural stem cells. Scientists were surprised to find it lives in the centrosome, an organelle in the cell’s interior that acts as chief architect for the organization of the cytoskeleton.

De-escalation of treatment strategies aims to minimize toxicity while maintaining efficacy.

In vertebrate retina cells, the majority of glucose is metabolized into lactate rather than being metabolized in the mitochondria. Understanding the mechanism behind this may improve our understanding of age-related macular degeneration.

A new form of synthetic DNA expands the information density of the genetic code, that likely preserves its capability for supporting life, according to a new study. By expanding the genetic alphabet from four letters to eight, researchers demonstrate the ability to double the information density in DNA.

Scientists working in a range of disciplines joined forces to identify a new approach to combat African sleeping sickness. Their research revealed a promising strategy to develop a suitable agent. This novel concept could also be employed in the future rational design of drugs for the treatment of other diseases.

Rubicon is a protein factor that suppresses autophagy by controlling a specific step in this pathway. This study found that Rubicon expression levels increased in an age-related manner in worm, fly, and mouse tissues.

Scientists from the University of Sheffield have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy.

Scientists have managed to restore hearing in an adult mouse model of DFNB9 deafness - a hearing disorder that represents one of the most frequent cases of congenital genetic deafness.

Scientists have developed nanopores that can be used to directly measure the mass of peptides, showing that a cheap and portable peptide mass spectrometer can be constructed using existing nanopore technology.

A new breakthrough identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.