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Mitochondrial Metabolite Channel Functions in Protein Transport
The research labs of the associate professor Dr. Thomas Becker and Prof. Dr. Nikolaus Pfanner from the Institute for Biochemistry and Molecular Biology at the University of Freiburg discovered a function of the metabolite channel of the mitochondrial outer membrane in protein transport.
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How Fibrosis Develops in Butterfly Syndrome
Butterfly syndrome is a rare inherited condition that causes the skin to become very fragile, and blister following minor friction. New data points to the major driver of fibrosis in these patients, giving therapeutic research new direction.
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Weight Loss Surgery Changes the Way Our Bodies Sense Food
Bariatric surgery alters patterns of digestion and absorption lower in the gut triggering production of higher levels of gut hormones, altering the way the gut senses food and nutrients.
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Decade Long Study Links Clusterin Protein to Cardiac and Metabolic Diseases
During a study spanning nearly a decade, researchers have linked the protein clusterin - for the first time - to many different facets of cardiometabolic syndrome risk through its actions in the liver.
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Protein Diversity Protects Chimpanzees From AIDS-like Viruses
Researchers are aiming to understand how immunodeficiency viruses are transmitted within and between species to reveal potential novel therapeutic avenues.
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Women’s Brains Appear Three Years Younger Than Men’s
A new study has reported that women’s brains appear to be about three years younger than men’s of the same chronological age, metabolically speaking. The findings could be one clue to why women tend to stay mentally sharp longer than men.
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Enzyme Warps Space to Break the Cellular "Speed Limit"
Researchers have found that rhomboid enzymes, which are special proteins that cut other proteins, are able to break the “cellular speed limit” as they move through the cell membrane.
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Evolution of Designer Enzymes
The impressively high conversion rates of natural enzymes partly result from increasing the catalytic activity of a selected few amino acid side chains through precise positioning within the protein binding cavity. Scientists have now demonstrated that such fine-tuning is also possible for "designer" enzymes with unnatural catalytic amino acids.
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Making an Impact with Meteorites
Scientists have simulated meteorite impacts in the lab and followed the resulting structural changes in two feldspar minerals with X-rays as they happened.
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Insect Microbiomes May be a Rich Source of Antibiotics
In an exhaustive search of microbes from more than 1,400 insects, scientists found that insect-borne microbes often outperformed soil bacteria in stopping some of the most common and dangerous antibiotic-resistant pathogens.
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