News

Cryo-electron microscopy imaging reveals an intricate arrangement of antibodies locked into a spiral structure with a parasite protein. The insights are key for improving malaria vaccine candidates.

One of the hallmark traits of Alzheimer’s disease, a debilitating disorder marked by memory deficits and general cognitive decline, is the accumulation in the brain of a protein called b-amyloid. Researchers have discovered a drug that blocks b-amyloid plaques from attaching to brain cells, preventing the extensive cell death.

Levels of antiphospholipid antibodies, which are associated with rheumatic diseases, are also elevated in myocardial infarction without any autoimmune co-morbidity.

Flaviviruses, such as dengue and Zika, were assumed to be symmetrical icosahedrons based on data from microscopes, but they might not be perfectly symmetrical after all.

Researchers have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia (AML) and a diagnostic test to determine which AML patients would most likely benefit from this treatment.

The newly discovered adhesion complex can provide answers to an as-yet unanswered question – how the cell can remain attached to the matrix during cell division.

This 3D neuro-model could help uncover early stage biomarkers of disease, in turn supporting earlier diagnosis and improving understanding of disease progression.

The structure of a central component of the Ebola virus has been imaged for the first time at near-atomic resolution.

A simple and inexpensive new test can diagnose patients with antibiotic-resistant strains of bacteria in a matter of minutes.

Defining the full spectrum of human disease associated with a biomarker is necessary to advance the biomarker into clinical practice.