News

Five new clinical sites, a new metabolomics core, and increased model organism capabilities among additions.

A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and bipolar disorder.

Findings suggest that protein ASTN2 is a key regulator of dynamic trafficking of synaptic proteins and lend support to the idea that aberrant regulation of protein homeostasis in neurons is a contributing cause of complex neurodevelopmental disorders.

Research sheds new light on the protective role of a naturally occurring mitochondrial peptide, known as humanin.

Blood test could help assess pilots' fitness to fly, and help police identify drowsy drivers in traffic accidents.

Using cryo-electron microscopy, scientists have obtained an unprecedented view of a gene-delivery virus, paving the way for further development of improved gene therapies.

Researchers have identified an independent prognostic factor - cancer/testis antigen 45 (CT45) - and have begun to elucidate it's actions. CT45 is associated with extended disease-free survival for women with advanced ovarian cancer.

Stanford scientists have measured the human “exposome,” or the particulates, chemicals and microbes that individually swaddle us all, in unprecedented detail.

Researchers from the Department of Biochemistry and Molecular Biology at the UAB and from the United Kingdom, for the first time describe the mechanism used by cells to optimise protein production in stressful situations through the altering of tRNA abundance.

The spatial and temporal dynamics of proteins or organelles plays a crucial role in controlling various cellular processes and in development of diseases. However, acute control of activity at distinct locations within a cell cannot be achieved. A new chemo-optogenetic method enables tunable, reversible, and rapid control of activity at multiple subcellular compartments within a living cell.