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Avoiding Late Diagnosis of Ovarian Cancer

Trial launched to support women who have chosen to keep their ovaries and fallopian tubes, despite ovarian cancer risk.
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Brain Receptor Protein is the Body's Fat 'Rheostat'

Scientists have identified the function of a protein that has been confounding metabolism researchers for more than two decades. And it may have implications both for treating obesity and for understanding weight gain during pregnancy and menopause.

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The Hearing Molecule

Ending a 40-Year Quest.
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How Do Muscles Know What Time It Is?

New study in mice reveals master regulator proteins which influence 24 hour metabolic rhythms in muscle cells.
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Researchers Target Protein That Protects Bacteria’s DNA ‘Recipes’

One challenge in the fight against bacterial disease is that pathogenic bacteria are extraordinarily resilient. Some bacteria accomplish this resilience by using a protein called Dps, which protects bacterial DNA from being damaged. In a new paper, researchers describe some of the unique characteristics of Dps that help bacteria survive stressful conditions. Their research may help lead to more targeted antibiotics and other drug therapies.

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CasPER Uses CRISPR to Diversify Enzymes

Scientists have invented a new method based on CRISPR-Cas9 technology that allows for flexible engineering of essential and nonessential enzymes without additional engineering. The Cas9-mediated Protein Evolution Reaction, or CasPER, could be of great importance for various aspects including the development of bio-based production.
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Synthetic Spider Silk is Strongest Yet

Spider silk is among the strongest and toughest materials in the natural world, as strong as some steel alloys with a toughness even greater than bulletproof Kevlar. Scientists have been have been unable to engineer a material that included most if not all of the natural silk’s traits. Until now.
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Common Disease Mechanism for ALS and Frontotemporal Dementia

Findings suggest mutations leading to accumulation of RNA-binding proteins to blame for disease, and could offer route for early diagnosis
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Scientists Discover Intricacies of Serotonin Receptor Crucial for Better Drugs

Researchers have figured out precisely why one drug binds to the serotonin receptor 5-HT2BR and activates it to cause heart problems while very similar drugs do not. They've also discovered why a third drug acts like a 5-HT2BR antagonist - it blocks the receptor's activity - while the very well-known similar hallucinogenic drug LSD does not.
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Progress toward Plugging an Antibiotic Pump

Each year in the U.S., at least 23,000 people die from infections caused by antibiotic resistant bacteria. Using computer modeling, researchers are developing the means to prevent some of those deaths. One way bacteria develop resistance is by producing pumps that spit out antibiotics, before they can do any damage. The researchers teased out the details of how one antibiotic pump works.
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