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Cortical mouse nerve cells.
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Subtypes and Sex Differences Discovered in ALS

Amyotrophic lateral sclerosis (ALS) is an almost always fatal neurodegenerative disease. Researchers have now discovered that ALS can be divided into subtypes and that there are clear differences in the molecular processes between men and women.
Cells.
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Hematopoietic Stem Cells Age Differently

Researchers at The Jackson Laboratory reveal that hematopoietic stem cells age differently in genetically identical mice, offering new pathways for interventions to preserve health with aging.
A scientist holding a vial.
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Cold-Sensing Protein’s Evolution Opens New Doors for Nonaddictive Pain Medication

ASU researchers uncovered new insights into the main human cold and menthol sensor TRPM8 (transient receptor potential melastatin 8), offering hope for future nonaddictive pain therapies.
Two halved blood oranges lie on a pile of the fruit.
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Storing Blood Oranges at Lower Temperatures Boosts Health Benefits

According to research, storing blood oranges at cool temperatures can increase antioxidant levels and preserve the firmness and sugar content of the fruit.
PET scans showing brain estrogen receptor (ER) density in a premenopausal (left) and a postmenopausal (right) woman.
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In Vivo Imaging Reveals Increased Estrogen Receptors in the Post-Menopausal Brain

A new study by Weill Cornell Medicine scientists sheds light on the brain activity changes that occur during menopause. The research used a pioneering brain imaging tool to track estrogenic activity in healthy women for the first time.
A doctor writing on a clipboard.
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Enzyme-Based Treatment Improves Lupus Outcomes in Animal Models

An enzyme-based treatment developed by Yale researchers mitigated autoimmunity and reduced death rates in both genetic and non-genetic mouse lupus models, a new study reveals.
A person's hand points to a brain scan.
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Poor Metabolic Health Is Associated With Memory and Thinking Problems

People with poor metabolic health are more likely to have worse brain health, experiencing memory and thinking problems, reports a new study.
A spoonful of sugar.
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New Biomimetic Concept Boosts the Synthesis of Stable Sugar Compounds

Researchers from the National University of Singapore (NUS) have developed a new biomimetic concept to convert naturally occurring sugars into diverse classes of stable glycosides and glycoproteins without using protecting-group chemistry.
A woman sitting on a bed clutching her stomach.
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Immune Dysfunction May Be a Novel Target for PCOS Therapy, Study Finds

A new study explores how polycystic ovary syndrome (PCOS) impacts the immune system, revealing that immune cell populations were affected across reproductive, metabolic and immunological tissues in different ways.
Protein structure.
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To Capture One of the Brain’s Fastest-Acting Proteins, Scientists Had To Slow It Down

New groundbreaking images of one of the brain’s fastest-acting proteins are providing critical clues that may lead to the development of targeted therapies to treat epilepsy and other brain disorders.
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