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Shivering Burns Fat Just Like Exercise
A key molecule that is released from fat as a signal to use fatty acids as metabolic fuel is stimulated by both exercise and being cold, a new study suggests.
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Real-Time Metabolomics in the Brain
Nagoya University-centered researchers develop novel system for in vivo real-time monitoring of metabolites in a living mouse brain.
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T Cell Biomarker Predicts Response to CAR T Cell Therapy
Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR) T cell therapy, and the answer is tied to how primed patients’ immune systems are before the therapy is administered.
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Gene Editing to Improve Blood Transfusions
Synthetic biologists have generated lab-grown red blood cells with rare blood group types that could one day be used to help patients who cannot be matched with donor blood.
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A Fatty Brain Could Be a Sign of Parkinson's
A collaborative team of researchers has found that higher levels of certain types of fat molecules in the brain may be an early sign of Parkinson’s disease (PD)
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New Breath and Urine Tests Detect Early Breast Cancer More Accurately
Researchers have isolated relevant data patterns to more accurately identify breast cancer biomarkers using two different electronic nose gas sensors for breath, along with gas-chromatography mass spectrometry (GC-MS) to quantify patterns of substances found in urine.
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Noninvasive Brain Tumor Biopsy on the Horizon
Taking a biopsy of a brain tumor is a complicated and invasive surgical process, but a team of researchers at Washington University in St. Louis is developing a way that allows them to detect tumor biomarkers through a simple blood test.
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E. Coli Rewired to Balance Growth with Protein Manufacture
Experts have equipped biotech workhorse bacteria with feedback control mechanism to balance growth with making protein products.
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First Detailed Structure of Telomerase Revealed
Over 30 years after its discovery, the detailed molecular structure of the longevity protein telomerase has been revealed, which may have implications for cancer treatment and bone marrow transplants.
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My Milkshake Brings All the Lipids to My Heart
An unorthodox study challenged volunteers with consuming a high-fat milkshake meal. A subsequent genetic analysis illuminated how genes affect our risk of high cholesterol and cardiovascular disease.
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