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First Detailed Structure of Telomerase Revealed
Over 30 years after its discovery, the detailed molecular structure of the longevity protein telomerase has been revealed, which may have implications for cancer treatment and bone marrow transplants.
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My Milkshake Brings All the Lipids to My Heart
An unorthodox study challenged volunteers with consuming a high-fat milkshake meal. A subsequent genetic analysis illuminated how genes affect our risk of high cholesterol and cardiovascular disease.
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The Protein Lasso Implicated in Breast Cancer
Certain types of RNA are implicated in the production of pro-breast cancer proteins. Now, a new study has shed light on the mechanism by which these RNAs manipulate DNA to produce these proteins.
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Flavins Keep a Handy Helper in Their Pocket
A team has now shown in detail how oxygen interacts with the flavin in an enzyme - revealing for the first time precisely how it works. Flavins play a key role in metabolic processes, in the immune system and in neural development in humans - and are equally important to bacteria, fungi and plants.
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Sweet Spot of Activity in Immune System Key to Fighting Cancer
Scientists have shown how stimulating a specific location on the surface of immune cells can be targeted with antibodies to help in their fight against cancer.
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Sheep Toxin Could Cause MS
Exposure to a toxin primarily found in sheep could be linked to the development of multiple sclerosis (MS) in humans, new research suggests.
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Blood Test To Determine When It Is Safe To Return To Play After A Sports-related Concussion
A high-sensitive blood test can aid concussed hockey players when it might be safe to return to play. In a study published by the journal Neurology, researchers at Sahlgrenska Academy have identified a superior blood-based biomarker for assessing subtle brain injury.
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Putting Proteins in Their Proper Place
Everything in the cell has its right place. This includes certain molecules called RNA-binding proteins. When these are misplaced, they can end up causing dangerous clumps that are typical of diseases like ALS. A new study has found a way to send these proteins home.
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Stable Beta-Amyloid Dimers Identified in Alzheimer’s Brains
A recent study exploited state-of-the-art mass spectrometry to provide the first direct evidence of beta-amyloid dimers in patients with Alzheimer’s disease and points to the potential of these molecules as biomarkers. Beta-amyloid dimers may be the smallest pathological species that trigger Alzheimer’s disease.
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Protein Target Identified That Could Prevent Strokes
Scientists have identified a protein, called GPR68, that senses blood flow and tells small blood vessels called arterioles when to dilate. The researchers believe medications that activate GPR68 could one day be useful to treat medical conditions, including ischemic stroke.
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