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Possible Biomarker to Identify Who Would Benefit from Immunotherapy
While immunotherapy has made a big impact on cancer treatment, the fact remains that only about a quarter of patients respond to these treatments. In a new study, researchers examined tissue samples from melanoma and ovarian cancer patients treated with immunotherapies and found a link between the percentage of antigen-presenting cells expressing PD-L1 and an objective clinical response to treatment.
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Longevity Protein Could Help Treat Diabetes
beta-Klotho, a protein that regulates longevity, could have therapeutic potential for diabetes and obesity.
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Protein's Role in Mitochondrial Metabolism Identified
EXD2, a protein previously thought to be localised to the nucleus, has a key role in the production of proteins by mitochondria.
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Glythera Appoints Chief Scientific Officer and Strengthens SAB
Dr Robert Lutz appointed as CSO to support development of next-generation PermaLink® Antibody Drug Conjugates. Dr Jon Roffey appointed to Scientific Advisory Board.
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Tweak to Technique Could Bolster Disease Detection
A team of Stanford researchers has developed a technique that they hope could more precisely detect diseases or disorders such as cancer or a heart attack.
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Proteasome Blocker Brings Glaucoma Gene Therapy Closer
An enhanced gene therapy technique that pairs a viral vector with a proteasome blockade has doubled the therapy's efficiency.
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Bile Acids Turn Cells from Fat-storing to Fat-burning
EPFL scientists have discovered a novel role for bile acids: converting energy-storing white fat depots into energy-expending beige fat.
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Dietary Fat Metabolism May Promote Metastasis
A new study has highlighted links between dietary fat and prostate cancer, suggesting a high-fat Western diet may encourage tumour metastasis.
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Multidisciplinary Study Suggests New Strategy for Drug Discovery
A joint industry/academia study of a cancer target protein reveals unusual relation between binding site flexibility and drug-target lifetime. The results, , suggest a new strategy for drug discovery.
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Concept Life Sciences appoints New Group Programme Manager and US Head of Sales
Key leadership appointments support integration of the Group and expansion in the US market.
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