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Multi-pronged Analysis Uncovers How Microbes Survive in Phosphorus-Poor Environments
A team has uncovered how certain soil microbes cope in a phosphorus-poor environment to survive in a tropical ecosystem. They used deep sequencing, mass spectrometry and metaproteomics to identify more than 7,000 proteins in each sample. Their novel approach could be applied in other ecosystems to study various nutrient limitations and inform agriculture and terrestrial biosphere modeling.
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Crystal Structure of Dopamine 2 Receptor Could Lead to Better Antipsychotic Drugs
Scientists at the UNC School of Medicine and UC San Francisco (UCSF) have solved the first high-resolution crystal structure of the dopamine 2 receptor (DRD2) bound to the antipsychotic drug risperidone, yielding a long-awaited tool for drug developers, psychiatrists, and neuroscientists.
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Artificial Sweeteners Could Help Treat Aggressive Cancers
Artificial sweeteners are used in diet drinks and foods but also could someday be used as treatments targeting carbonic anhydrase IX (CA IX), a protein associated with aggressive cancers.
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42: The Answer to Life, the Universe and... the Number of Proteins in a Cell?
Scientists have worked out the exact number of protein molecules contained in a cell and the answer seems strangely familiar...
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Synthetic Auxin Reveals Importance In Plants
A new synthetic hormone promises to tease apart the many different roles of the plant hormone auxin and could lead to a new way to ripen fruit.
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Protein Key That Opens a Closed Genome Discovered
Pax7, a transcription factor, is able to open up compacted genome segments to allow cell growth to occur properly.
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Algorithm Unearths Over 1000 Antibiotic Proteins in a Few Hours
The algorithm identified 10 times more peptide variations than all previous discoveries combined, aiding the hunt for new antibiotics.
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Protein That Helps Keep Breast Cancer Dormant Identified
A protein kinase that stops breast cancer cells growing and spreading has been outlined in new research.
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Barrier to Liquid Biopsies Overcome with Blood Stabilization Technique
A new technique that prolongs the lifespan of blood samples could be a breakthrough for liquid biopsy assays.
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Could New Treatment Strategy Overcome Drug Resistance in Testicular Cancer?
In a new study, scientists show that a targeted drug blocking the action of a cancer-driving protein can kill testicular cancer cells and, alongside chemotherapy, could reverse drug resistance.
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