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Discovering a Protein’s Role in Gene Expression

Beyond providing new insights into the regulation of gene expression, the findings have important implications for metastatic melanoma, and several neuro-developmental syndromes.
Obese and Anorexic Women Have Low Levels of ‘Feel Good’ Neurosteroid content piece image
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Obese and Anorexic Women Have Low Levels of ‘Feel Good’ Neurosteroid

Researchers have found that women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, a metabolite of the hormone progesterone. Gas chromatography and mass spectrometry were used to pick up extremely small levels of these chemicals in blood serum, saliva and brain tissue.
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Detecting New Proteins in Active Mice

By using innovative labeling methods, researchers have developed a technique to measure newly synthesized proteins in the active mouse brain allowing observations of real time changes in the proteome.
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Potential Biomarker for Early Detection of Alzheimer's

Findings may also provide a means of homing drugs to diseased areas of the brain to treat AD, Parkinson's disease, as well as glioblastoma, brain injuries and stroke.

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New Disease Discovered That Causes Kidney Failure

A group have discovered an insidious new autoimmune disease, anti-brush border antibody (ABBA) disease, that causes kidney failure, utilising techniques including proteomics and immunostaining.
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Method Developed to Identify Thousands of Protein Complexes and Their Location, in One Shot

Scientists have developed a method for getting at harder-to-reach proteins and identifying thousands of them at one time. The discovery may speed up the ability to understand complex protein interactions and how they control functions such as growth, tolerance to heat and drought, and yield.

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Not So Different After All: Human Cells and Hardy Microbes Share Common Ancestor

A team have found striking parallels between how archaeal cells and more complex cells, including humans’ and animals’, package and store their genetic material.
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Fat Cells May Inactivate Chemotherapeutic Drug

A recent study showed that adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes.
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New "Sugar-Glass" Film Uses Viruses to Kill Harmful Bacteria in Food

Scientists report that they have developed an antibacterial "sugar-glass" coating in which viruses that destroy bacteria are embedded and are kept stable for up to three months. The coating could someday be used in the food packaging and processing industries to help prevent food-borne illnesses and deaths.
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Multiple Mutations Drive Cancer Drug Resistance

Blood-based cancer tests have revealed the complex genomic landscape of non-small cell lung cancers.
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