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A train of evolution from monkey descendants to a human, with microbes travelling between.
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Gut Microbes May Have Helped Fuel the Evolution of Large Brains

Researchers show gut microbes may have fueled brain evolution by optimizing energy use. Experiments revealed that microbes in large-brained primates like humans and squirrel monkeys promoted higher energy expenditure.
Illustration of spinal cord stimulation
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Predicting the Effectiveness of Spinal Cord Stimulation

Spinal cord stimulation is often a last resort for those with intractable chronic pain. A new 10-minute brain scan gives doctors a much-needed biomarker to discuss with patients considering spinal cord stimulation.

A muscled woman faces away from the camera.
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Study Captures the Aging Process of Muscles at the Cellular Level

As muscles age, their cells lose the ability to regenerate and heal after injury. Researchers have created the most comprehensive picture yet of this process.
Looking down a microscope to plant cells with stomata.
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Researchers Identify Which Proteins Open and Close Stomata in Response to Drought

Researchers have unraveled the cellular mechanisms behind stomata opening and closing.
Cancer cells.
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Six-Gene Pattern Predicts Drug Success for Multiple Myeloma Patients

Researchers identified a six-gene pattern predicting venetoclax response in multiple myeloma. This genetic insight allows for personalized treatments, improving patient outcomes.
Rod shaped bacteria.
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Bile Composition Changes To Help Combat Intestinal Infections

Brigham and Women’s researchers uncover bile’s dynamic role in intestinal infection defense, revealing compositional changes that enhance gut protection. Using a mouse model, they identified over 800 bile metabolites altered by pathogens.
Sea anamone.
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How Sea Anemones Maintain Shape While Regenerating

Researchers discovered that starlet sea anemones reshape their entire bodies during regeneration to maintain their original proportions. Using spatial transcriptomics, the team identified enzymes active throughout the body that realign tissues.
A woman holding her head.
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Scientists Uncover Key Stress Pathway Driving Migraines

UT Health San Antonio researchers discovered that stress-induced migraines are driven by PACAP38 binding to MrgprB2 on mast cells, leading to inflammatory responses and trigeminal sensitization.
Colourised scanning electron micrograph of Escherichia coli, grown in culture and adhered to a cover slip.
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How Bacteria Outwit Antibiotics by Altering Ribosomal Structures

Researchers uncovered a novel bacterial resistance strategy where E. coli modifies ribosomal structures to evade antibiotics like streptomycin and kasugamycin. Using nanopore sequencing, the study revealed ribosomal changes that prevent effective dru
Cells.
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Protein Mobility May Be a Key Driver of Decreased Cellular Function in Chronic Disease

A study identifies "proteolethargy," reduced protein mobility caused by oxidative stress, as a unifying mechanism in chronic diseases. The findings suggest that impaired protein movement disrupts cellular functions.
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