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Ancient DNA Reveals Down Syndrome in Historical Populations
A new study scoured ~10,000 ancient genomes in search of trisomies, such as Down Syndrome. Combined with archeological analyses, the data reveal how these infants were perceived in ancient societies.
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Fighting HIV With RNA
Researchers have developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
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Understanding the Molecular Mechanisms Behind Hibernation in Mammals
Researchers have characterised changes in the structure of motor proteins, called myosins, and energy consumption that occur during hibernation, highlighting key differences in large and small hibernators.
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High-Protein Diet Could Drive Heart Disease
A new study published in Nature Metabolism investigated the potentially adverse effects of a high protein diet, which is often promoted as a “healthy lifestyle”.
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First Human Trial Shows “Wonder” Material Is Safe To Develop
A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests.
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10 Polygenic Scores for Chronic Disorders Progress to the Clinic
By analyzing millions of small genetic differences, researchers can calculate a polygenic risk score for disease. Ten of these risk scores have been validated for clinical use.
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Common B Vitamin Linked to Heart Disease
Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.
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Targeting “Undruggable” Proteins Opens New Doors for Neurodegenerative Disease Treatment
Researchers unveil groundbreaking research with the potential to alter the treatment landscape for neurodegenerative diseases (NDs). The study introduces a pioneering approach aimed at combating conditions such as Alzheimer’s disease.
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Bulls Offer Insight Into Male Fertility
Researchers have found genes in the reproductive organs of bulls that influence fertility. The findings can be transferred to humans, as these genes are also present in men.
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Ancient Retroviruses Supported the Evolution of Vertebrate Brains
A retrovirus-derived genetic element is to thank for myelin production – and by extension, large brains – in vertebrates.
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