Bio-Rad Announced the Capability of its MicroRotofor™
News Jul 12, 2006
Bio-Rad Laboratories, Inc. has announced the capability of its MicroRotofor™ cell instrument to enrich low-abundance proteins for biomarker discovery.
Biomarker discovery requires the ability to dig deeper into the proteome to find proteins that are of relatively low-abundance.
The effective study of low-abundance proteins often requires a fractionation step to reduce sample complexity and improve the concentration of low-abundance proteins.
With the MicroRotofor cell, formerly undetectable proteins can be enriched to levels that allow analysis by 2-D gel electrophoresis/mass spectrometry (2-D/MS) and liquid chromatography/tandem mass spectrometry (LC-MS/MS), methods that are commonly used in proteomics for the separation and identification of proteins.
The MicroRotofor cell is applied upstream of both 2-D/MS and LC-MS/MS workflows.