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Blunting Pain’s Emotional Component

News   Mar 19, 2019 | Original Press Release from Washington University in St. Louis

 
Blunting Pain’s Emotional Component

Pain researchers at Washington University School of Medicine in St. Louis have shown in rodents that they can block receptors on brain cells that are responsible for the negative emotions associated with pain, such as sadness, depression and lethargy. The findings could lead to new, less addictive approaches to pain treatment. In these PET images of rat brains, kappa opioid receptors (dark blue) are active in response to pain (right) in a part of the brain linked to emotion, but are relatively inactive when pain-free (left). Credit: Washington University School of Medicine

 
 
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