Does the gut microbiome offer new therapeutic options for brain diseases?
News Jul 11, 2016
An interview with David Perlmutter, MD -
The surprising and potentially wide-ranging effects that the levels and diversity of bacteria living in the gut have on overall human health, inflammation, and specifically brain health are the focus of a provocative interview with Dr. David Perlmutter in Alternative and Complementary Therapies.
In the interview, titled "The Role of Microbiome Diversity in Brain Health and Inflammation," David Perlmutter, MD, FACN, ABIHM, University of Miami School of Medicine, Florida, discusses the role of the microbiome in conditions such as Alzheimer's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and autism. He points to ALS as an example of how research on the underlying cause of certain diseases may be shifting from a focus on the brain to the gut. Future treatments for diseases such as ALS could involve fecal transplants to restore the integrity and correct the balance of bacterial composition of the intestines.
Regarding the link between the microbiome and Alzheimer's disease, autoimmune and inflammatory disorders, and the overuse of antibiotics to treat infection, Dr. Perlmutter states, "I hypothesize that our diets today are affecting our microbiomes and therefore challenging our immune systems. Our diets are setting us up for these opportunistic issues [infections]."
Note: Material may have been edited for length and content. For further information, please contact the cited source.
et al. The Role of Microbiome Diversity in Brain Health and Inflammation: A Clinical Conversation with David Perlmutter, MD, FACN, ABIHM, and Robert Rountree, MD. Alternative and Complementary Therapies, Published June 7 2016. doi: 10.1089/act.2016.29052.dpe
Researchers Democratize Neuroscience by Making it Easier to Share Brain Imaging DataNews
Researchers have developed a set of tools to make one critical area of big data research — that of our central nervous system — easier to share.READ MORE
Neuroscientists Identify The Retrosplenial Cortex as an Integrator of Vision and Head MovementNews
Study highlights role of primary visual cortex in integrating head and visual movement signalsREAD MORE
So Hot it Hurts: Ion channel trio underlying painful heat sensation foundNews
Researchers show that acute noxious heat sensing in mice depends on a triad of transient receptor potential (TRP) ion channels: TRPM3, TRPV1, and TRPA1.READ MORE