How sleep helps us learn and memorize
News May 28, 2015
Sleep is important for long lasting memories, particularly during this exam season. Research published in PLoS Computational Biology suggests that sleeping triggers the synapses in our brain to both strengthen and weaken, which prompts the forgetting, strengthening or modification of our memories in a process known as long-term potentiation (LTP).
Researchers led by Sidarta Ribeiro at the Brain Institute of the Federal University of Rio Grande do Norte, Brazil, measured the levels of a protein related to LTP during the sleep cycle of rats. The authors then used the data to build models of sleep-dependent synaptic plasticity.
The results show that sleep can have completely different effects depending on whether LTP is present or not. A lack of LTP leads to memory erasure, while the presence of LTP can either strengthen memories or prompt the emergence of new ones.
The research provides an empirical and theoretical framework to understand the mechanisms underlying the complex role of sleep for learning, which involves selective remembering as well as creativity.
Note: Material may have been edited for length and content. For further information, please contact the cited source.
Wilfredo Blanco , Catia M. Pereira , Vinicius R. Cota , Annie C. Souza , César Rennó-Costa, Sharlene Santos, Gabriella Dias, Ana M.G. Guerreiro, Adriano B.L. Tort, Adrião D. Neto, Sidarta Ribeiro. Synaptic Homeostasis and Restructuring across the Sleep-Wake Cycle. PLoS Computational Biology, Published May 28 2015. doi: 10.1371/journal.pcbi.1004241
Exposure to Low Levels of BPA during Pregnancy Can Lead to Altered Brain DevelopmentNews
New research in mice provides an explanation for how exposure to the widely used chemical bisphenol A (BPA) during pregnancy, even at levels lower than the regulated “safe” human exposure level, can lead to altered brain development and behavior later in life.READ MORE
Catalyst Can Degrade Alzheimer's-Related Amyloid Peptide Under Near-Infrared LightNews
A new, biocompatible photooxygenation catalyst that can selectively oxygenate and degrade the pathogenic aggregation of Alzheimer's disease (AD)-related amyloid-β peptide (Αβ) under near-infrared (NIR) light irradiation has been developed.READ MORE
Comments | 0 ADD COMMENT
World Congress on Pathology and Laboratory Medicine
Sep 10 - Sep 11, 2018
World Congress on Advances in Addiction Science and Medicine
Sep 24 - Sep 25, 2018