We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

ApoE4 Toxicity Mechanism in Alzheimer's Solved

News   Sep 20, 2017 | Original Story from the Washington University School of Medicine, St. Louis

 
Mechanism of ApoE4 Gene Toxicity in Alzheimer's Disease Neurodegeneration Solved

Parts of the brain important for memory have atrophied in a mouse carrying the high-risk Alzheimer's gene ApoE4, leaving a large fluid-filled hole in the brain (white area in photo at left), compared with a much smaller one in a mouse without the gene (right). A new study led by researchers at Washington University School of Medicine in St. Louis shows that the presence of ApoE4 exacerbates brain damage related to the Alzheimer's protein tau. Credit: Yang Shi

 
 
 

RELATED ARTICLES

Rearranging Chromosomes – Does It Affect Their Function?

News

Molecular biologists long thought that domains in the genome’s 3D organization control how genes are expressed. After studying highly rearranged chromosomes in fruit flies, researchers now reveal that while this is the case for some genes, their results challenge the generality of this for many others.

READ MORE

Put Down That Flyswatter: Insects Feel Pain Too

News

Scientists have known insects experience something like pain since 2003, but new research published today from Associate Professor Greg Neely and colleagues at the University of Sydney proves for the first time that insects also experience chronic pain that lasts long after an initial injury has healed.

READ MORE

Gaining Insight Into Sun-induced DNA Damage and Cell Repair

News

A team has published a breakthrough article that provides a better understanding of the dynamic process by which sunlight-induced DNA damage is recognized by the molecular repair machinery in cells as needing repair.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Drug Discovery Genomics Research Neuroscience

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE