We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

ApoE4 Toxicity Mechanism in Alzheimer's Solved

News   Sep 20, 2017 | Original Story from the Washington University School of Medicine, St. Louis

 
Mechanism of ApoE4 Gene Toxicity in Alzheimer's Disease Neurodegeneration Solved

Parts of the brain important for memory have atrophied in a mouse carrying the high-risk Alzheimer's gene ApoE4, leaving a large fluid-filled hole in the brain (white area in photo at left), compared with a much smaller one in a mouse without the gene (right). A new study led by researchers at Washington University School of Medicine in St. Louis shows that the presence of ApoE4 exacerbates brain damage related to the Alzheimer's protein tau. Credit: Yang Shi

 
 
 

RELATED ARTICLES

Is There a Link Between Herpes and Alzheimer's?

News

Possible links between herpes and Alzheimer's disease have been assessed in a recent review.

READ MORE

The Building Blocks of an Electronic Brain

News

Computer bits are binary, with a value of 0 or 1. By contrast, neurons in the brain can have all kinds of different internal states, depending on the input that they received. This allows the brain to process information in a more energy-efficient manner than a computer. A new study hopes to bring the two closer together.

READ MORE

Inside a Bully's Brain

News

Duke-NUS researchers have discovered that a growth factor protein, called brain-derived neurotrophic factor (BDNF), and its receptor, tropomyosin receptor kinase B (TrkB) affects social dominance in mice. The research has implications for understanding the neurobiology of aggression and bullying.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Drug Discovery Genomics Research Neuroscience

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE