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Mitochondrial Dysfunction May Play a Part in Fragile X Syndrome

News   Feb 12, 2019 | Original Press Release from the University of Wisconsin-Madison

 
Mitochondrial Dysfunction May Play a Part in Fragile X Syndrome

Microscope images from the lab of Xinyu Zhao compare neurons with normal or mutated fragile X gene. With the mutation, mitochondria were shorter and failed to join together. A loss of fusion impairs the neuron’s ability to communicate and plays a role in causing fragile X symptoms. Scale bar shows 10 microns.Credit: Adapted from Zhao lab, Waisman Center, University of Wisconsin-Madison

 
 
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