Parent satisfaction with clinical trial on treating aggressive behavioral disorders
News Apr 20, 2015
A new study of families participating in a clinical trial to treat children with severe physical aggression explored the factors affecting parent satisfaction with the research study. Parents' overall satisfaction with the clinical trial experience and the relationship between the parent satisfaction and their child's treatment group or response to therapy are reported in an article in Journal of Child and Adolescent Psychopharmacology.
The Treatment of Severe Childhood Aggression (TOSCA) study included behavioral management training for parents of children with severe physical aggression, disruptive behavior disorder, or attention-deficit/hyperactivity disorder. The children all received a psychostimulant and either a placebo or the antipsychotic drug risperidone.
"These findings indicate high levels of satisfaction with TOSCA study involvement and, taken together with previous pediatric psychopharmacology social validity studies, suggest high levels of support for the research experience," according to the authors. "These findings may inform research bioethics and may have implications for the deliberations of institutional review boards."
Note: Material may have been edited for length and content. For further information, please contact the cited source.
E.V. Rundberg-Rivera, L.D. Townsend, J. Schneider, C.A. Farmer, B. Molina, R.L. Findling, K.D. Gadow, O.G. Bukstein, L.E. Arnold, D.J. Kolko, K.A. Buchan-Page, N.K. McNamara, C. Michel, A. Austin, H. Kipp, R.R. Rice, M.G. Aman. Participant Satisfaction in a Study of Stimulant, Parent Training, and Risperidone in Children with Severe Physical Aggression. Journal of Child and Adolescent Psychopharmacology, Published April 17 2015. doi: 10.1089/cap.2014.0097
All in a Droplet: Atomic Resolution of ALS Protein ResolvedNews
Researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone.READ MORE
Pupil Size Couples to Cortical States to Protect Deep Sleep StabilityNews
Researchers have found that mice pupil size fluctuates during sleep. They also show that pupil size is a reliable indicator of sleep states.READ MORE
A Place to Think: Persistent neuronal activity in human prefrontal cortex links perception and actionNews
Neuroscientists have tracked the progress of a thought through the brain, showing clearly how the prefrontal cortex at the front of the brain coordinates activity to help us act in response to a perception.READ MORE