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Researchers Identify Mechanism Behind Inherited Neuropathy Charcot-Marie-Tooth Disease

News   Jun 09, 2020 | Original story from Forschungsverbund Berlin e.V.

 
Researchers Identify Mechanism Behind Inherited Neuropathy Charcot-Marie-Tooth Disease

In contrast to control animals (on the far left), animals with loss of the Rab35 protein in Schwann cells exhibit demyelination of nerve fibers: myelin outfoldings (yellow arrow); myelin degeneration (green arrow); "tomacula" - focal thickening of the myelin sheath (red star). Credit: Alessandra Bolino, IRCCS Ospedale San Raffaele

 
 
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