New Huntington's Disease Stem Cell Model

News   Feb 06, 2018 | By Julia Evangilou Strait for WUSTL

 
Stem Cells From Huntington's Patients Made Into Neurons, Recapitulate the Disease

Pictured are reprogrammed cells from a 71-year-old patient with Huntington's disease. Originally skin cells, these have been converted into medium spiny neurons, the cell type affected in Huntington's disease. Sampling skin cells from patients and converting them directly into neurons affected by the disorder is a new tool to help understand why nerve cells die in this fatal condition.

 
 
 

RELATED ARTICLES

Mechanism Controlling Multiple Sclerosis Risk Identified

News

Researchers at Karolinska Institutet have now discovered a new mechanism of a major risk gene for multiple sclerosis (MS) that triggers disease through so-called epigenetic regulation. They also found a protective genetic variant that reduces the risk for MS through the same mechanism.

READ MORE

Scientists Discover Fundamental Rule of Brain Plasticity

News

When one synapse strengthens, neighboring synapses weaken immediately based on the action of a crucial protein called Arc.

READ MORE

The Case of the Missing Brain Region is Solved

News

Researchers demonstrate that subplate neurons survive, and in fact become part of the adult cerebral cortex.

READ MORE

 

Comments | 0 ADD COMMENT

Like what you just read? You can find similar content on the communities below.

Cell Science Drug Discovery Neuroscience

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE
 

We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy