Study finds cardiorespiratory fitness contributes to successful brain aging
News Apr 27, 2015
Cardiorespiratory fitness may positively impact the structure of white matter in the brains of older adults. These results suggest that exercise could be prescribed to lessen age-related declines in brain structure.
The findings, which appear online in the Annals of Clinical and Translational Neurology, are the first to show a relationship between fitness and brain structure in older adults, but not younger adults.
The researchers compared younger adults (age 18-31) to older adults (age 55-82). All participants had MRIs taken of their brains and their cardiorespiratory (heart and lung) fitness was measured while they exercised on a treadmill. The researchers found cardiorespiratory fitness was positively linked to the structural integrity of white matter fiber bundles in the brain in the older adults, while no such association was observed in younger adults.
"We found that higher levels of cardiorespiratory fitness were associated with enhanced brain structure in older adults," explained corresponding author Scott Hayes, PhD, assistant professor of psychiatry at Boston University School of Medicine and the associate director of the Neuroimaging Research for Veterans Center at the VA Boston Healthcare System. "We found that physical activities that enhance cardiorespiratory fitness, such as walking, are inexpensive, accessible and could potentially improve quality of life by delaying cognitive decline and prolonging independent function," he added.
According to the researchers these results provide evidence of a positive association between fitness and brain structure in older adults. "We hope this study provides additional motivation for older adults to increase their levels of physical activity, which positively impacts health, mood, cognition and the brain." They caution that additional research is needed to track changes in fitness and brain structure over time, as well as clarify the impact of specific exercise programs (such as strength, aerobic or combined training) or dose of exercise (frequency, intensity, duration) on white matter microstructure.
Note: Material may have been edited for length and content. For further information, please contact the cited source.
Scott M. Hayes, David H. Salat, Daniel E. Forman, Reisa A. Sperling, Mieke Verfaellie. Cardiorespiratory fitness is associated with white matter integrity in aging. Annals of Clinical and Translational Neurology, Published Online April 24 2015. doi: 10.1002/acn3.204
Sometimes in life there are special places that seem to stand out to us - that inconspicuous street corner where you were kissed for the first time, for example. Before the kiss you had never even noticed that corner. Our attitude towards these places changes - they become valuable to us. But could this also happen purely by the power of imagination rather than by the experience itself?READ MORE