We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Study finds that genetic ancestry partially explains one racial sleep difference
News

Study finds that genetic ancestry partially explains one racial sleep difference

Study finds that genetic ancestry partially explains one racial sleep difference
News

Study finds that genetic ancestry partially explains one racial sleep difference

Read time:
 

Want a FREE PDF version of This News Story?

Complete the form below and we will email you a PDF version of "Study finds that genetic ancestry partially explains one racial sleep difference"

First Name*
Last Name*
Email Address*
Country*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

A new study clearly establishes a partial genetic basis underlying racial differences in slow-wave sleep, suggesting that it may be possible to develop sleep-related therapies that target specific genetic variants.


Using a panel of 1,698 ancestry informative genetic markers, the study found that greater African genetic ancestry was associated with lower amounts of slow-wave sleep in African-American adults. African ancestry explained 11 percent of the variation in slow-wave sleep after adjustment for potential confounders. Although a similar association was observed for delta power, no association with African ancestry was observed for sleep duration and efficiency.


“Our data are the first to show that race differences in slow-wave sleep may have an independent and significant genetic basis,” said senior author Martica Hall, professor of psychiatry at the University of Pittsburgh. “Although all humans have the same set of genes, variations within the genes sometimes follow population-specific patterns. By identifying the specific genetic variants that influence slow-wave sleep, we can eventually develop population-specific treatment approaches and therapies for sleep.”


Study results are published in the August issue of the journal Sleep.


Led by Hall and lead author Indrani Halder, the research team analyzed data from a community-based sample of 70 African-American adults and 101 European Americans with a mean age of about 60 years. Objective sleep data were gathered by polysomnography. Blood samples for genotyping were collected, and DNA was isolated following standard protocols. 


According to the authors, African-Americans have varying proportions of genetic admixture and exhibit a wide range of African genetic ancestry. Among African-American study participants, percentage of African ancestry ranged between 10 percent and 88 percent, with a mean of 67 percent.


Note: Material may have been edited for length and content. For further information, please contact the cited source.

American Academy of Sleep Medicine   press release


Publication

Hall MH et al. African Genetic Ancestry is Associated with Sleep Depth in Older African Americans.   Sleep, Published August 2015. doi: 10.5665/sleep.4888


Advertisement