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This Receptor Mediates the Effects of Chronic Stress in the Brain

News   Jun 05, 2020 | Original story from Florida Atlantic University

 
This Receptor Mediates the Effects of Chronic Stress in the Brain

The image shows a reporter protein, tdTomato, in a coronal section of the brain containing hippocampus. Researchers engineered the tdTomato in the IL-1R gene so the expression of IL-1R can be visualized. In addition to expression in endothelial cells, which forms vasculature, the image shows IL-1R in the dentate gyrus (resembling teeth, hence dentate), on both side of the brain. The dentate IL-1Rs are on neurons, allowing the inflammatory cytokine IL-1 to directly signal these neurons. Credit: Florida Atlantic University

 
 
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