This Week on NeuroScientistNews: 16 March – 20 March
News Mar 20, 2015
Memory consolidation and sleep; new stroke research; brain networks in schizophrenia, and more.
Sleep is thought to contribute to memory consolidation, and observed patterns of neural activity are known to repeat as sharp wave ripples (SPW-Rs) during slow wave sleep. However, it is unknown if these SPW-Rs during sleep actually reflect a replay of spatial information or not. In a recent publication in Nature Neuroscience (de Lavilleon et al., 2015), the authors investigate this by dissociating neural activity from the physical location of mice and demonstrating causally that place cell activity is representative of location.
Scientists at The University of Manchester have made an important new discovery about the brain’s immune system that could lead to potential new treatments for stroke and other related conditions.
Mayo Clinic research finds direct evidence of gadolinium deposition in neuronal tissues following intravenous administration of gadolinium-based contrast agents used in MRI exams. The findings were recently published online in the journal Radiology.
People with a severe form of schizophrenia have major differences in their brain networks compared to others with schizophrenia, bipolar disorder and healthy individuals, a new study from the Centre for Addiction and Mental Health (CAMH) in Toronto, Ontario, Canada shows.
Epilepsy is a very prevalent neurological disorder. Approximately one-third of patients are resistant to currently available therapies. A team of researchers under the guidance of the Institute of Cellular Neurosciences at the University of Bonn has discovered a new cause to explain the development of temporal lobe epilepsy: At an early stage, astrocytes are uncoupled from each other. This results in the extracellular accumulation of potassium ions and neurotransmitters, which cause hyperexcitability of the neurons.
Therapeutic Avenue for Parkinson's Disease?News
A new potential therapeutic avenue for Parkinson's disease. This research is unusual given that it focuses on senescence in astrocytes, so called "helper" cells that perform a variety of tasks, from axon guidance and synaptic support to control of the blood brain barrier and blood flow.READ MORE
Using Epigenetic Signatures and Machine Learning to Improve DiagnosisNews
Unique epigenetic signatures for nine neurodevelopmental disorders have been identified, lending to a better method of diagnosis for disorders with much clinical overlap.READ MORE
Valence Mapped: Brain study reveals roots of desire and dislike in the amygdalaNews
Researchers map the amygdala's distinct but diverse and dynamic neighbourhoods where feelings are assigned.READ MORE