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Hyperactive Brain Cells May Be to Blame When Antidepressants Don't Work

News   Feb 01, 2019 | Original Press Release from the Salk Institute

 
When Neurons Get the Blues

When neurons get the blues. This artistic image shows neurons derived from pluripotent stem cells of antidepressant (SSRI) resistant depressed patients. SSRI-resistant patient neurons display hyperactivity in response to serotonin. The study reveals potential mechanism associated with SSRI-resistance in major depressive disorder (MDD). The image is modified from Figure 2c of Vadodaria et al., Molecular Psychiatry, 2019. Credit: Salk Institute

 
 
 

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