Latest Posters
Poster
"In-vitro studies on hydroxamic acid- CT DNA binding"
In vitro studies of five the interaction between five different derivatives of hydroxamic acids, N-phenyl 2,4dichloro phenoxybutyro, N-m-tolyl 2,4 dichlorophenoxyglutero, N-m-tolyl-4-chlorophenoxyaceto, N-m-chloro-phenyl-tertiarybutylbenzo and N-p-tolyl-iso-valero hydroxamic acids and calf thymus DNA was investigated under simulated physiological condition.
Poster
Antioxidant and Free Radicals Scavenging Activity of Biomolecules: Hydroxamic Acids
In the present poster attention is focused towards the investigation of antioxidant and free radicals scavenging activity of N-aryl substituted hydroxamic acids by DPPH method which is based on the reduction of alcoholic DPPH solutions in presence of a hydrogen donating antioxidant, hydroxamic acids.
Poster
Efficacy of Gene Therapy in Restoring Vision in Leber's Congenital Amaurosis
The research reviews current knowledge of the genetic causes of Leber's congenital amaurosis (LCA) and the development of a gene therapy intervention for LCA. The efficacy as well as the limitations of this form of treatment are evaluated in detail and recommendations are made for the future directions of gene therapy for Leber's congenital amaurosis.
Poster
Recent Technical Developments in the Standardized Separation and Measurement of Extracellular Vesicles
We present robust and practical solutions for the standardization of EV isolation and concentration measurement. EV concentration also needs to have a defined size range. With these solutions, significant improvement in the reproducibility and comparability of results between different researchers is possible.
Poster
High Titre BacMam viruses improve transduction efficiency of mammalian cells
We present a method for producing high titre BacMam virus vectors for the efficient transduction of mammalian cells.
Poster
Novel Approaches to High-throughput Measurements of Replicative Lifespan in Yeast by Microfluidic Size Sorting and Genetic Engineering
Development of a high-throughput screen utilizing a microfluidic device and a linearly growing yeast strain to simultaneously test the influence of various drugs on the replicative lifespan of yeast.
Poster
Automated Fluorescence Detection and Imaging of RNA Species in Live Cells
This poster describes the detection and quantification of RNA species in Live cells through automated imaging.
Poster
The Longest Way Round is the Shortest Way Home: HTS Assay Development for Complex Multi-domain Protein Kinases
This study strongly supports the possibility to overcome the major bottlenecks in the production of long kinase recombinant forms, in order to perform drug discovery programmes with proteins more closely preserving the structural and functional properties of the native enzymes.
Poster
Identification and Characterisation of Novel Positive Allosteric Modulators of the Galanin 2 Receptor
An HTS against GalR2 was carried out to find novel PAMs to treat neuropathic pain.
Poster
Validation of a 3-Dimensional Human Liver Microtissue Model for Long-term Hepatotoxicity Studies
Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of drug commonly used as analgesics and antipyretics, as well as for management of rheumatological disorders. They are one of the most highly prescribed drug families around the world, and consequently, along with antimicrobial agents, are the most frequent causes of druginduced liver injury (DILI) (Bjornsson et al., 2010).
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