Latest Posters

The growing use of RNA-based vaccines and therapies has focused much attention and effort on developing conditions for maximizing the yield and efficiency of the in vitro transcription (IVT) reactions used to produce mRNA. IVT procedures involve the biosynthesis of RNA from a linear DNA template containing an appropriate transcription promoter. But how do different buffer conditions and nucleotide concentrations impact the IVT reaction?

Membrane proteins are a notoriously difficult class of proteins to express, purify and characterize. Expression levels of membrane proteins in mammalian expression systems, the preferred system to generate native-like post-translational modifications, are often so low that yields are unsuitable for the intended downstream uses.

Nucleic acid amplification and detection techniques are highly valuable tools that can be used across a wide range of applications... Real-time PCR, also known as quantitative PCR (qPCR), is the gold-standard for sensitive, specific detection and quantification of nucleic acid targets.

Cells establish their function, identity and state through the careful orchestration of complex molecular mechanisms leading to gene expression. To characterize cells more accurately, it is important to evaluate gene expression at both transcript and protein levels.

Download this poster to learn more about unbiased spatial gene expression,
application of spatial gene expression plus immunofluorescence validation and targeted analysis.

Core facilities in academic institutions provide services and instrument access to research labs that by themselves lack the expertise and/or resources to perform metabolomics experiments.

Download this poster to discover how ITC requires minimal assay development and sample preparation, allows early determination and elimination of false positives and can be used to identify fragments that will form a high-resolution co-crystal with the target protein.

Download this poster to discover how the SpatialOMx workflow using timsTOF fleX provides detailed in situ characterization of bioactivity across different tumor cell subpopulations.

Download this poster to discover a new and improved MALDI-TOF MS workflow for the screening of synthetic chemical reactions.

Download this poster to discover a novel approach for detection of cGAS activity.