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Infections have detrimental effects on wound healing leading to chronic wound formation. The use of labskin,a living skin model, in combination with mass spectrometry imaging, provides a good model for assessing wound healing factors.

Can we use computational methods to identify previously unknown off-targets of PARP inhibitors that can explain their observed differences?

Automated robotic sample preparation with hyphenated dual LC-SWATH/MS analysis for lipids and polar metabolites.

Here we evaluate the ability to detect changes in phosphorylation levels of ERK and CREB following treatment with Aβ using the SH-SY5Y neuroblastoma cell line.

In the studies of origins of life, plausible synthetic reaction pathways to form biological relevant molecules, or building blocks of proto‐bilayer lipids, protein, RNA, and DNA in the primitive environment have been investigated intensively.

Ionic co-crystals of lithium salicylate with organic proline (LISPRO) showed better safety and pharmacokinetic profile of lithium in plasma and brain of wild-type and transgenic Alzheimer mice model compared to lithium salts.

The method allows for automated determination of total fat content and quantitative analysis of saturated and unsaturated cis- and trans- fatty acids of different chocolate products.

Salting out, adding a solvent, altering the pH are various means to precipitate proteins. In a subsequent two-step process, the mixture is then centrifuged and the supernatant is pipetted off to separate it from the precipitate.

Metabolomics is a viable method for identifying compounds associated with NAFLD. In this investigation, high-quality data facilitate the identification of key metabolites differentiating normal versus diseased species.

Extraction of Analytes of Toxicolgical Interest from Plasma with Enhanced Matrix Removal-Lipid (EMR-Lipid) Material.