Ethnopharmacological Evaluation of Radal (leaves of Lomatia hirsuta) through Metabolite Profiling and Isolation of 2-Methoxyjuglone.
Poster Feb 26, 2007
To evaluate the efficacy of the traditionally used herbal remedy Radal a metabolite profile of the original plant material was established. The EtOAc extract of the leaves and found to be active against the pathogenic fungus Candida albicans (MIC = 8 µg/ml). Cinnamic acid (2) and vanillic acid (5) were identified as the major constituents in the tea by GC-MS along with other phenolic derivatives.
Investigating the Effects of Fructose Consumption and Inadequate Copper Intake on Nonalcoholic Fatty Liver DiseasePoster
Metabolomics is a viable method for identifying compounds associated with NAFLD. In this investigation, high-quality data facilitate the identification of key metabolites differentiating normal versus diseased species.READ MORE
A Tissue-based Proteomic Study of VEGFR2 in Human Term PlacentasPoster
VEGFR2 is the main regulator of placental angiogenesis and at term is localized in endothelial cells (EC) of the villous vasculature. VEGFR2 immunoprecipitation (IP) of membrane proteins, extracted from the fetal compartment, isolated 30 proteins that were identified by proteomic analysis.READ MORE
RAMclust/RAMsearch: efficient post-XCMS feature clustering and annotation of MS-based metabolomics datasetsPoster
Chromatographically coupled mass spectrometry is a powerful tool for profiling, semi-quantitatively or quantitatively, a breadth of small molecules with sensitivity and selectivity.READ MORE