Fully Automated LC-MS/MS-based Determination of Bosentanand its Metabolites in Dried Blood Spots using the SCAP™ DBS System

Poster

Published: December 7, 2010

Fully Automated LC-MS/MS-based Determination of Bosentanand its Metabolites in Dried Blood Spots using the SCAP™ DBS System content piece image

The advantages of DBS are:

•   Only low amount (25 μL) of test material needed
•   Minimal sample processing needed
•   Sample storage and shipment at ambient temperature possible

However automation of the DBS workflow is needed to enable a through put that can compete with conventional plasma analysis. This poster details how the SCAP™ DBS System allows fully-automated DBS analysis via LC-MS/MS without need of time-consuming spot punching and manual extraction.