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Molecular Devices Unveils Next-Generation SpectraMax Multi-Mode Microplate Readers

Scientist operating a SpectraMax® iD5e Multi-Mode Microplate Reader in a laboratory setting.
Credit: Molecular Devices.
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Molecular Devices, LLC., announced the launch of SpectraMax® iD5e and
SpectraMax® iD3s Multi-Mode Microplate Readers. Honoring a legacy of product
line reliability and strength, the SpectraMax Multi-Mode Microplate Readers
have been transformed with next-generation innovation to improve research
capabilities and provide unparalleled flexibility for a wide range of assays
and applications.


"For over 40 years, our industry-leading microplate readers
have empowered researchers to advance protein and cell biology, breaking
barriers to novel discoveries,” said Mary Duseau, President of Molecular
Devices. “Our new SpectraMax iD5e and SpectraMax iD3s readers are designed to
meet the evolving needs of modern laboratories, support the holistic
exploration of cellular processes through advanced multi-omics research, and
enable customers to push the boundaries of complex biology.”


The SpectraMax iD5e and iD3s Multi-Mode Microplate Readers both
offer tunable monochromator-based measurements with temperature control, making
them ideal for researchers conducting absorbance, fluorescence, luminescence,
and advanced detection assays. Common features include dual injectors with
SmartInject® Technology for precise reagent mixing, as well as user-installable
gas mixers and advanced shaking capabilities for live cell assays, providing
flexibility and efficiency for diverse applications.

Microplate Reader Capabilities Compared

The SpectraMax iD3s reader was engineered for a streamlined design
and affordability, making it ideal for labs seeking cost-effective solutions
without compromising performance. The reader excels in performing ELISA,
nucleic acid and protein quantitation, cell viability, and microbial assays.
Its fully tunable monochromator wavelength selection offers assay flexibility,
while optional upgrades—such as dual injection, advanced shaking, and
environmental controls—enhance its versatility. The SpectraMax iD3s reader also
features over 200 preconfigured protocols and a user-friendly interface,
ensuring ease of use and enhanced productivity for various common assays.


The SpectraMax iD5e reader is an enhanced solution with hybrid
optics, combining tunable monochromator and filter-based measurement
capabilities. This reader is equipped to handle absorbance, fluorescence,
luminescence, time-resolved fluorescence (TRF), and tunable fluorescence
polarization (FP). Unique features of the SpectraMax iD5e reader include
automatic filter identification using NFC functionality, western blot detection
capabilities, and QuickSync data push technology for seamless data transfer.
The microplate reader's flexible temperature control and intuitive touch screen
interface make it ideal for busy, multi-user labs, ensuring reliable and
high-performance results across an array of assays.

Intuitive Data Acquisition

SoftMax® Pro Software—the industry’s most cited microplate reader
software—powers both models and can be upgraded to a GxP version that assures full compliance with FDA and EudraLex guidelines. SoftMax Pro GxP Software streamlines workflows to optimize data integrity, analysis, and reporting, with secure, traceable electronic recordkeeping. Expert installation and validation services ensure operational specifications are met, supporting researchers in achieving reliable and compliant results.


The SpectraMax iD5e and iD3s microplate readers will be on display in booth #1407 at BioProcess International, September 15–18, 2025, Boston, Mass.