Otava Ltd Presents new Protein Kinase Focused Libraries

• New Aurora B Kinase Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries. Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this Aurora B kinase focused library is composed of 2069 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family.

• New Cyclin Dependent Kinase 2 (CDK2) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries. Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this CDK2 focused library is composed of 1281 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Death-Associated Protein Kinase 2 Dapk-2 Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries. Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this DAPK-2 focused library is composed of 2012 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

Our library design method has been created to model a physical process of molecular binding as accurately as it is possible in today’s science.

• New Extracellular Signal-Regulated Kinase 2 (ERK2) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries. Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this ERK2 focused library is composed of 2053 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Proto-Oncogene Tyrosine-Protein Kinase Abl1 Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries. Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this ABL1 focused library is composed of 2048 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Serine/Threonine-Protein Kinase Chk1 Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries. Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this CHK1 focused library is composed of 1946 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries. Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this VEGFR2 focused library is composed of 2235 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Fibroblast Growth Factor Receptor 1 Tyrosine Kinase (FGFR1K) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries.  Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this FGFR1K focused library is composed of 1761 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Cyclin Glycogen Synthase Kinase-3 (GSK3) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries.  Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this GSK3 focused library is composed of 980 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Janus Kinase 2 (JAK2) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries.  Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this Jak2 focused library is composed of 2190 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New P38 Map Kinase Alpha Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries.  Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this p38 MAP Kinase Alpha focused library is composed of 2221 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New 3-Phosphoinositide-Dependent Kinase-1 (PDK-1) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries.  Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this PDK-1 focused library is composed of 1975 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Phosphatidylinositol 3-Kinase (PI3K) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries.  Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this PI3K focused library is composed of 2040 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).

• New Camp Dependent Protein Kinase (PKA) Focused Library:

This library has been created as a part of a project aimed at designing of a large set of protein kinase focused libraries.  Taking its origin from of OTAVA’s in-house collection of 500,000 compounds, this PKA focused library is composed of 1877 compounds which were selected by computational estimation of their interaction with one specific member in a protein kinase family (sharp-focusing approach).