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Respected Synthetic Biology Group Chooses G:BOXChemi XT4

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Syngene has announced that its G:BOXChemi XT4 is being used by scientists at the University of Edinburgh to accurately quantify DNA and proteins from bacteria engineered to produce metal nanoparticles. This work is contributing to speeding up throughput of research on novel methods of processing toxic metals from contaminated soil.

Researchers in the Horsfall Laboratory at the University of Edinburgh in Scotland are using a G:BOXChemi XT4 multi-application imager to analyze agarose gels of bacterial DNA stained with the green fluorescent dye SafeView™. They are also utilizing the G:BOXChemi XT4 to image SDS-PAGE gels and chemiluminescent Western blots of bacterial proteins used to make nanoparticles of heavy metals such as arsenic and platinum.

This is allowing scientists there to accurately quantify DNA to genetically engineer bacteria that are able to produce metal nanoparticles from material extracted from plants grown on land contaminated with toxic metals. These nanoparticles of platinum and arsenic, for example, are valuable, and using bacteria to further process the plant material adds value to the decontamination process.

Michael Capeness, Research Technician in the Horsfall Laboratory, stated: “We’re engineering bacteria that are capable of reducing accumulated toxic metals from plant extracts grown on contaminated soil into solid metal nanoparticles. To do this we utilize a number of different molecular biology techniques and image a range of gel and blot types.”

Capeness continued: “There are nine researchers using this imager in our lab and this means we need a flexible system which is quick and simple to set up each time. We assessed two analyzers and chose the G:BOXChemi XT4 as it met all our requirements.”

Laura Sullivan, Syngene’s Divisional Manager, commented: “We are delighted that our imaging equipment is helping researchers at the University of Edinburgh to speed up the throughput of their research. For scientists in core facilities wanting a flexible, easy to use imager which can accurately analyze both fluorescently labelled DNA, as well as chemiluminescent proteins the G:BOXChemi XT4 imaging system is the perfect, cost-efficient solution.”