Thermo Fisher Scientific Introduces New Tools to Study Active Serine Hydrolases

Product News

Published: April 17, 2011

Want a FREE PDF version of this product news?

Complete the form below and we will email you a PDF version of "Thermo Fisher Scientific Introduces New Tools to Study Active Serine Hydrolases"

First Name*

Last Name*

Email Address*

Country*

Company Type*

Job Function*

Would you like to receive further email communication from Technology Networks?

Listen with

Speechify

0:00

Thank you. Listen to this article using the player above. ✖

Read time:

Thermo Fisher Scientific, has announced the introduction of novel reagents for the study of active serine hydrolases. The Thermo Scientific ActivX Serine Hydrolase Probes contain a fluorphosphonate (FP) element that specifically binds to the active site of serine hydrolases.

The probes enable enrichment of serine hydrolase enzymes and determination of enzymatic activity using fluorescent SDS-PAGE, Western blot or mass spectrometry (MS) workflows.

Three ActivX® Serine Hydrolase Probes are available. The ActivX TAMRA-FP Probes can be used to label and detect serine hydrolase activity in samples using fluorescent gel imaging, capillary electrophoresis or MS.

The ActivX Azido-FP Probes can be used in combination with phosphine- or alkyne-derivatized tags for detection or enrichment. Lastly, the ActivX Desthiobiotin-FP Probes can be used for detection and enrichment of active-site-labeled proteins by Western blot and MS.

The ActivX Serine Hydrolase Probes provide sufficient reagent for 100 labeling reactions or 10 pull-down reactions. The probes store easily at -80°C for up to one year.