Thermo Scientific Introduces Pierce High Capacity Endotoxin Removal Resin
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Thermo Fisher Scientific has introduced the Thermo Scientific Pierce High Capacity Endotoxin Removal Resin for the cleanup of protein that is injected or transfected into cells or animals.
The Pierce® High Capacity Endotoxin Removal Resin combines porous cellulose beads and an FDA- approved food preservative, poly (ε-lysine), as an affinity ligand to selectively bind endotoxins.
Endotoxin levels in protein samples are reduced by greater than 99 percent in as little as one hour using a spin cup format, and protein recovery is greater than 85 percent.
The Pierce High Capacity Endotoxin Removal Resin peptides have a high affinity for the charged glycol-groups of an endotoxin, while the particle pores help trap endotoxins.
The modified polylysine affinity ligand eliminates the toxicity concerns associated with alternative technologies that use polymixin B ligands and sodium deoxycholate buffers.
The Pierce High Capacity Endotoxin Removal Resin is available in bulk slurry packages for researchers who want to pack their own columns. This resin can be reused up to five times.
The resin is also available in convenient, single-use, spin-column formats, which provide a fast one-hour protocol.
