Waters Debuts Class of Mass Spectrometry Technology at ASMS

Waters Corporation has announced that it is introducing mass spectrometry technology that differentiates sample ions by mass, size and shape at the 54th American Society of Mass Spectrometry Conference on Mass Spectrometry, May 28 – June 1.

The Waters^® Synapt™ High Definition MS™ (HDMS™) System is designed for researchers working at the limits of conventional mass spectrometry and who need to further characterize and define complex samples.

The Synapt HDMS system employs ion-mobility technology and software to enable the analysis of sample ions differentiated by size and shape, as well as molecular mass.

This additional dimension of separations fidelity leads to improved specificity and sample definition, meaning scientists can extract more information about their samples including the detection of previously undetected constituents.

A key feature of this system is the patented Waters Triwave™ technology, a unique methodology for combining highly-efficient, ion-mobility based measurement and separations with accurate mass quadrupole time-of-flight mass spectrometry.

Operational control and data acquisition and processing are performed through Waters MassLynx™ Software.

Shipments of the mass spectrometer are expected to begin in the second half of 2006.

Waters collaborator Professor Carol Robinson of the University of Cambridge, Cambridge, England, has evaluated the technology and in a peer-reviewed article in Science magazine she and her colleague, post-doctoral researcher Bandon Rutolo, disclosed how the technology helped to convincingly demonstrate that gas phase structures of intact multi-protein complexes, though devoid of bulk solvent, are essentially equivalent to native solvated structures.

In addition to numerous poster and oral presentations highlighting this technology, Waters is also presenting a luncheon seminar at ASMS entitled An Introduction and Insight Into the Theory and Mechanisms of High Definition Mass Spectrometry, Wednesday, May 31, from 12:30 - 1:15 p.m. in Room 204 of the Washington State Convention and Trade Center.