XenoTech Now Provides Pooled Human Liver Homogenate
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This test system is ideal for metabolism identification when responsible enzymes are not known, proteomic assays, enzymatic activity studies, etc.
Sekisui XenoTech's human liver homogenate is comprised of tissue from 20 donors that is homogenized, centrifuged at low speed to remove connective tissue, large pieces of cell membranes and intact cell nuclei, and diluted to a constant protein concentration. By removing the additional centrifugation steps that are typical in S9 or microsomal preparations, the resulting fraction is rich with drug metabolizing enzymes and proteins.
Homogenate from other species and tissue is available from Sekisui XenoTech as a custom preparation.