Comprehensive Immune Checkpoint-Related Products for Immuno-Oncology Therapy

Immune checkpoint molecules play a crucial role regulating immune responses, maintaining a balance between fighting diseases and preventing excessive inflammation. These molecules either enhance or suppress immune reactions, which has made them a key target in cancer therapy, particularly through immune checkpoint blockade. Despite the promising potential of immune checkpoint inhibitors, challenges such as various patient responses and resistance development. In response, ongoing efforts involve the development of bispecific antibodies and the combination of immune checkpoint inhibitors with other treatments. This dynamic landscape has driven the creation of a range of immune checkpoint-related products, encompassing high-quality proteins, inhibitor screening kits, stable cell lines, and PK assay kits. These products provide researchers with essential tools to advance immunotherapy effectively. • Immune Checkpoint Proteins: Our high-quality proteins, including stimulatory and inhibitory molecules, are rigorously verified for purity using MALS or HPLC and for bioactivity through ELISA/SPR/FACS. Each batch maintains consistency through strict QC testing, making them ideal for immune studies, antibody screening, and pharmacokinetic applications. • Inhibitor Screening Kits: Designed for efficiency, our kits utilize a competitive ELISA method for screening potential inhibitors. Featuring high-sensitivity assays with unique in-house biotinylated proteins, these kits simplify the process with a pre-validated 4-step ELISA procedure. They are tailored for preliminary screening of small molecule inhibitors, peptides, and quality control in drug development, providing researchers with reliable and accurate tools for inhibitor screening and validation. • Overexpressed Stable Cell Lines: Our cell lines guarantee verified bioactivity through FACS, providing robustness and high protein productivity for various research applications.