Lipidomics for Biotechnology, Pharma and Academia
Lipids are ubiquitous to almost every biological process. Major diseases are already known to involve lipids (cardiovascular diseases, Alzheimer’s disease, diabetes, cancer, and many more). The introduction of multi-parametric lipidomic data is bound to revolutionize clinical diagnostics, drug development and academic research, providing an accurate read-out for the health and disease status of an individual.
Lipotype Shotgun Lipidomics
Expensive methodology, poor data quality and lack of bioinformatics tools – Lipotype Shotgun Lipidomics Technology has overcome these hurdles. It combines decades of experience in sample preparation, MS analysis and bioinformatics to deliver absolute quantification of thousands of lipids present in multiple sample types – from organelles and exosomes, bacteria, yeast and other microorganisms, cultured cells and blood plasma to tissues and organs: muscles, liver, brain, and many others. We achieve this with an unprecedented throughput at an affordable price.
Lipotype Shotgun Lipidomics can be applied for
- Drug discovery (mode-of-action studies, target validation, effect on lipid metabolism)
- Biomarker identification (pharmacodynamic, pharmacokinetic, CDx)
- Proof-of-concept studies in early phases of drug development
- Clinical screenings and diagnostics
- Topical drug development and validation for dermatology
- Intervention studies for development of nutraceuticals
Highlights of our Technology
Lipotype Shotgun Lipidomics covers more than 2,300 individual lipids in 30 different lipid classes. Lipids are identified at the structural level of lipid subspecies (including fatty acid composition of lipids).
The quantification is achieved using lipid class-specific internal standards. Therefore, results are expressed in absolute values.
Our technology allows for the analysis of hundreds of samples per day, offering unprecedented delivery time of as fast as two weeks for complete results and associated reports.
Various Sample Types
From organelles and exosomes, bacteria, yeast and other microorganisms, cultured cells and blood plasma to tissues and organs – our technology supports a wide range of sample types and requires only minimal amounts of sample per analysis, e.g. 1 µl of blood plasma.
Lipotype Shotgun Lipidomics technology is highly reproducible, robust and reliable with a technical variation < 10%.
New Level of Data Analysis
The extensive know-how in data mining, machine learning, and multi-factorial regression analyses of our team led to LipotypeZoom and advanced statistical reports to access your in-depth lipidomics data.
Lipotype delivers comprehensive, absolutely quantitative lipid analysis services for clinical and biological samples on a high-throughput scale. Drawing on many years of cutting edge research experience, Lipotype offers high quality lipid analysis services for a wide range of customers and applications including biomarker identification for clinical researchers, pharma and biotech companies, functional food development for the food industry, claim support for the cosmetics industry, as well as for the small-scale profiling needs of academic researchers.
Lipotype is a spin-off company from the Kai Simons and Andrej Shevchenko labs of the world-renowned Max-Planck-Institute of Molecular Cell Biology and Genetics in Dresden, Germany.