Cytiva

But how do you purify small volumes for preclinical and clinical studies without losing too much to processing or leaving capacity unused?

To meet these needs, we developed scalable capture and polishing chromatography steps for recombinant AAV. Here we highlight the polishing step.

Biotherapeutic drugs are complex and can perform their function through interactions with more than one target molecule. During development and quality control, a range of analytical technologies are used to characterize biotherapeutic drugs in terms of their structural integrity and activity. Ligand-binding assays are relevant for characterization and quantitation of the functional drug, however current analytical approaches may no longer be sufficient for analysis of emerging drug modalities.
Biacore™ assays are based on ligand binding and used in development and characterization of drug product using active concentration measurements, target binding, potency (E50)
and Fc receptor (FcR) analysis.

This webinar will review how kinetic characterization of biological interactions can guide the selection of best-in-class detector molecules to enhance lateral flow diagnostics and outline the benefits of characterizing and selecting your lateral flow antibodies using SPR technology.

In this Teach Me in 10, we are joined by Dr. Peter Guterstam, Product Manager at Cytiva. Peter explores how core bead technology can be used to achieve high recovery rates in your chromatography workflow.

Biacore™ 8 series SPR systems

Your discovery — accelerated. With maximized capacity. High quality binding data to meet your toughest challenges in screening, characterization, process optimization, and quality control.

Andrew Schulman explores why we need allogeneic therapies, the importance of collaboration to keep the momentum, and challenges and predictions for the future.

When designing your own lateral flow assay (LFA), it is important to consider the critical variables that impact accuracy and reliability, including detection reagents, assay materials and manufacturing methods.

Watch this webinar to learn more about applications for screening and characterizing antibody and antibody fragments plus a label-free technology which uses surface plasmon resonance (a biophysical technology) for characterizing antibodies.

Aiming to improve exosome purification process that is currently slowing adoption of promising gene therapies and other new modalities.