Anticancer Therapies – News and Features

A novel CAR T-cell therapy has benefitted patients with relapsed acute lymphoblastic leukemia, showing high response rates in a Phase Ib/II trial.

A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions.

Using a gene-screening method, Stanford Medicine researchers have uncovered why chemotherapy can damage heart cells and have identified a drug to keep the heart cells beating.

A tiny, four-fingered “hand” folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them.

Researchers revealed that checkpoint inhibitors, a powerful cancer immunotherapy, impair B cell function, reducing antibody diversity and increasing infection risk. They suggest immunoglobulin replacement therapy as a preventive measure.

NYU Langone researchers found cancer cells resist chemotherapy in low-glucose environments by conserving pyrimidines and blocking apoptosis pathways. These adaptations minimize drug effectiveness by altering metabolism.

A wearable TENS device delivering low-voltage electrical currents significantly reduced pain and fatigue in long-COVID patients, improving mobility by 8% in fast walking tests.

Researchers explore how established agricultural pest management strategies could be adapted to address cancer therapy. The pioneering method opens new possibilities for controlling drug resistance and improving patient survival.

Nanoparticles coated with polymers made with natural sugars could reduce the immune response to cancer treatment, making it more effective.

UCLA researchers have developed a new approach to treating glioblastoma by combining genetic and functional profiling to predict tumor responses to therapies. The team showed promising results in tumor shrinkage.