Biomarkers – News and Features

Researchers at the Keck School of Medicine developed a tau PET imaging cut-point to identify early Alzheimer’s signs. The cut-point distinguished cognitive impairment in Hispanic and non-Hispanic white participants.

This article explores how cancer biomarkers improve early detection, guide treatments and predict outcomes to transform personalized cancer care.

Aggressive forms of acute myeloid leukemia (AML) remain challenging to treat, especially in patients with FLT3-ITD mutations. Researchers have identified a key epigenetic regulator that promotes leukemia cell growth by promoting MYC activation.

A team discovered that patients with Dementia with Lewy Bodies (DLB) have significantly lower levels of α-synuclein in their blood compared to healthy individuals. This finding could lead to a blood-based biomarker for early diagnosis.

Researchers have found that lung cancer patients who have a combination of high levels of depression and inflammation at diagnosis are later found with continuing depressive symptoms in the next several months.

A new, far less invasive capsule sponge test to detect early cancer signs could safely replace the use of regular endoscopies for over half of all patients with Barrett’s oesophagus, a known precursor to oesophageal cancer.

Spatial transcriptomics is just the start – learn why spatial proteomics is essential to fully understand cell function and disease mechanisms in this thought piece from Dr. Nikhil Rao, CCO at Syncell.

A study by the University of Gothenburg found that newborns have elevated levels of p-tau217, a protein fragment linked to Alzheimer’s disease. The protein’s rise in infants is thought to support brain development, particularly in synapse formation.

Researchers from Lurie Children’s Hospital identified several proteins in the umbilical cord blood of preterm infants that signal early onset sepsis. Their findings offer a noninvasive, objective way to diagnose sepsis.

Researchers from Michigan State University and their partners have found new biological clues that could help doctors detect prostate cancer and heart disease earlier.