Cell Culture – Webinars and Online Events

This webinar will explore how we can isolate and expand patient-derived intestinal organoids in culture. By combining these organoids with scaffolds, we can generate functional intestinal mucosal grafts which demonstrate a proof-of-concept for subsequent clinical translation and future use in patients.

Metabolomics, the investigation of small molecules present in a biological system, finds application in diverse biomedical and industrial research. In large-scale applications, targeted profiling of metabolites is employed as it provides confident measurements for compounds of interest.

Water is used for almost all applications in the laboratory. Impurities are found in all tap water and can have a negative effect on scientific analyses. Water that is adequate for rinsing vessels may not be adequate for analytical work.

Human induced pluripotent stem cell (iPSC)-derived retinal organoids are an emerging tool for the study of retinal development, disease modeling and drug discovery.

Ancillary materials (AMs), also called raw materials in Europe, are components, reagents, and materials used in the manufacturing of cell, gene, and tissue-engineered (CGT) therapies but are not intended to be present in the final product formulation.

This talk will describe using a combined experimental approach of gene expression profiling, exosome analysis, and high-content imaging in 2D and 3D liver cell culture models to evaluate early IDILI events and risk factors contributing to overt liver injury observed in the clinic.

Watch this webinar to discover the benefits of gene synthesis, how gene optimization boosts expression of your protein as well as the fastest and easiest way to assemble your DNA constructs.

Microphysiological Systems (MPS), also known as organ-on-a-chip, generate human-relevant 3D cell culture models whose phenotypes and functions mimic individual in vivo organs. When therapeutics are added, these models can generate results that translate into clinical outcomes more reliably than standard in vitro techniques.

The manufacturing process for cell and gene therapies is complex and can contain process-related impurities from multiple organisms. A commercial host cell protein (HCP)-ELISA kit is often not available for the cell line or is not suitable for the specific process due to a low HCP coverage. Development of a process-specific ELISA can be unfeasible as the product often requires a short development time.

During this webinar, we will discuss our hiPSC-derived cortical and sensory neurons, co-culture and their electrophysiological characterization using microelectrode arrays (MEA). The focus is on the development of disease models, co-culture, pharmacology and neurotoxicity screening.