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Data Reporting, Compliance and Integrity – News and Features

The pathogenic bacterium Pseudomonas aeruginosa breaching through the respiratory epithelia of a human lung microtissue model, captured via Scanning Electron Microscopy.
News

Organoids Reveal How Pathogens Invade Human Lung Tissue

Using human lung microtissues a team at the University of Basel has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated strategy to break through the lungs’ line of defense.
A hand holding a test tube in front of a 3D structure of a DNA helix.
News

Bilateral Gene Therapy Restores Hearing in Children with Inherited Deafness

A new clinical trial in Shanghai, China, in partnership with Mass Eye and Ear researchers, demonstrated the restoration of hearing in both ears in five children born with autosomal deafness caused by mutations in the OTOF gene.
Floating cells on an orange background.
Article

Challenges and Solutions in Cell Therapy Development

In this article, we explore how researchers are tackling some of the challenges preventing cell therapies from being more widely used. We also outline advances in manufacturing and regulatory approval processes that will help expand patient access to life-changing treatments.
Female doctor and patient seated, smiling and looking at a tablet.
Article

Strengthening a Commitment to Diversity and Inclusion in R&D With the Help of Novel Machine Learning Approaches

In this article, we discuss how a deep learning framework can specifically address real-world challenges to enhance site selection while seeking to improve trial diversity.
Gloved hand using tweezers to remove a test tube from liquid nitrogen.
Article

Overcoming Obstacles in Automating Cryogenic Storage

This article explores the challenges and strategies involved in transitioning to automated cryogenic storage systems. From assessing current infrastructure to gaining organizational buy-in and selecting appropriate containers, follow these steps to help ensure a successful transition to automated cryogenic storage.
A seaside town with a beach and sea in the foreground.
Article

Protecting Our Oceans Starts With Testing – Part One

The analytical testing of our oceans is paramount to check for the presence and concentrations of pollutants, helping protect human health and biodiversity. The resulting data can also help to ensure compliance and give insights into climate change.
Cell therapy.
News

Cell Therapy Treatment Effectively Treats Immune-Compromised Children

In a first-of-its-kind clinical trial, researchers found that intravenous therapies made from virus-specific T-cells (VST) can effectively treat immunocompromised pediatric patients, far surpassing the current standard of care.
A gloved hand pipettes liquid into a petri dish
Article

Microbial Monitoring for Biopharma Manufacturing

Contamination is a significant issue for bioprocessing as it results in loss of time, money and effort. This article will explore the pivotal role of microbial monitoring in upholding product safety and quality standards within the biopharmaceutical industry.
Purple strand of mRNA.
Industry Insight

Creating the Right Environment for mRNA To Thrive

Scott Ripley explores how realizing the potential of mRNA therapeutics will require the standardization of processes, manufacturing agility and collaboration between industry, academia and government bodies.

A collection of many different pills.
Industry Insight

Using AI To Get Medicines to Patients Faster

To find out more about AI in pharma, Technology Networks spoke with Roger Palframan, head of US Research and digital for Early Solutions at UCB.
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