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Exosomes – News and Features

Cancer cells adhered to a surface.

Cell-to-Cell Communication in Cancer

We typically think of a cancerous tumor as a bunch of abnormal cells gone rogue, but the situation is more complicated. This article will explore cell-to-cell communication’s role in cancer development, its influence on metastasis and how research is expanding our knowledge of the disease.
Neuron shapes shown in gold.

Brain Cell Activation in Mice Increases Life Span

Activating a critical communication pathway that links the brain and fat tissue may slow the effects of advancing age.
Mouldy strawberries.

Plants Use “Trojan Horse” To Fight Mold Invasions

UC Riverside scientists have discovered a stealth molecular weapon that plants use to attack the cells of invading gray mold.
A scientist places blood test vials into a rack.

Blood Test Could Identify Individuals at Risk of Developing Parkinson’s Disease

A newly developed blood test could identify the pathology that triggers Parkinson's disease before symptoms occur, allowing clinicians to screen those at high risk of the disease.
A neuron.

Why Tackling Neurodegeneration Requires Global Partnerships

Neurodegenerative diseases are characterized by synapse dysfunction and the aggregation of proteins in the brain, which ultimately lead to neuronal loss. This article will review the studies and methods powering our growing understanding of the mechanisms behind neurodegenerative disease.
Cancer immunotherapy. A white cancer cell is attacked by two small red T cells.

Improved mRNA Therapy Enhances Glioblastoma Response to Immunotherapy

Researchers have loaded extracellular vesicles with therapeutic mRNA, and shown how they can be used to enhance immunotherapy responses in glioblastoma.
Stem cells.

Fitness of Cells Used in Cell Transplants Improved

Researchers found exposing cells to a small molecule drug improved their fitness during hematopoietic stem cell transplants, which could broaden access and improve outcomes for ex vivo gene therapy.
A diagram of a uterus.

Stem Cell-Derived Components May Treat Underlying Causes of PCOS

Polycystic ovarian syndrome (PCOS) affects millions of women and is notoriously difficult to treat. A new treatment has been unveiled that may improve multiple PCOS symptoms.
Blue cells labelled with green and red dyes.

New Insights Into Cause of Poor Wound Healing in Diabetics

Defective exosomes, which shuttle signals between cells, can drive inflammation and impair wound healing in diabetic patients, according to a new study.
A cell dividing.

How Do Extracellular Vesicles Impact Human Health?

Researchers wanted to understand how cells react to these extracellular vesicles (EVs) produced by different cell types and at varying concentrations.