Gene and Cell Therapy – News and Features

Drug discovery efforts have expanded beyond the traditional approaches of small molecules and antibodies to include cells. This article explores the use of microfluidic methods for high-throughput screening of cell-based drug products.

Three-dimensional models allow researchers to better represent complex tissues and cell-cell interactions. This article explores the cell models currently used by researchers to understand disease and aid drug discovery.

Researchers have developed a novel method using CRISPR to study transcription factors affecting blood cell development. The Perturb-multiome approach identifies critical DNA regions linked to blood disorders.

A novel cell therapy approach using natural killer cells pre-complexed with a bispecific antibody, was safe and generated strong response rates for patients with refractory CD30-positive lymphoma, according to a new study.

USC Viterbi researchers have engineered a new immune cell that, when activated by ultrasound, can continuously sense and destroy cancer cells for extended periods.

To help improve gene therapy, a multidisciplinary team has generated a comprehensive atlas that researchers can use to select the most effective viral vehicle for their target organ.

To explore how the CGT landscape is evolving, Technology Networks spoke with Betty Woo, vice president of Cell, Gene and Advanced Therapies at Thermo Fisher Scientific.

The limitations of traditional cryopreservation are becoming increasingly apparent. In this interview, Alastair Carrington, CEO of Atelerix, explores how hypothermic preservation technology is transforming biopreservation.

A recent study demonstrated the potential of gene therapy to restore motor capacity in an ultra-rare disease, megalencephalic leukoencephalopathy with subcortical cysts (MLC), even when treatment begins after symptom onset.

To accelerate the development of cell-based regenerative therapies that could one day reverse heart damage, researchers have taken cardiac cells to space to understand how they proliferate and survive.