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Liquid Biopsies – News and Features

Clinical laboratory worker handling test tubes containing blood.

Association for Molecular Pathology Publishes Best Practice Recommendations for Liquid Biopsy Assay Validations

The Association for Molecular Pathology has published a set of 13 best practice recommendations for validating and reporting clinical circulating tumor DNA or liquid biopsy assays and their related scientific publications.
Ovarian cancer tumor microenvironment.

New Blood Test Detects Early-Stage Ovarian Cancer

A new study on human tissue and plasma shows the blood test may distinguish between cancerous and benign pelvic masses with up to 91% accuracy, surpassing other commercially available tests.
A purple-gloved hand holding two test tubes filled with blood.

ctDNA Analyses Could Help Guide Immunotherapy for Non-Small Cell Lung Cancer Patients

Measuring ctDNA could offer a new approach to identifying non-small cell lung cancer patients in greater need of additional treatments during immunotherapy.
A medical professional taking blood from a patient.

ctDNA Shows Promise as a Prognostic Biomarker for Advanced Melanoma

Measuring circulating tumor DNA may lead to alternative treatment options and better outcomes for patients with advanced BRAF-negative melanoma, report investigates in The Journal of Molecular Diagnostics.
Two vials of blood.

Liquid Biopsy Could Guide Treatment Decisions for Oligometastatic Lung Cancer

A new study could help doctors decide the best treatment strategy for patients with lung cancer that has spread beyond the original tumor but has not spread all over the body.
A woman breastfeeding an infant.

Early-Stage Breast Cancers Detected From Breastmilk

Researchers have shown for the first time that breast milk from breast cancer patients contains tumor DNA, known as circulating tumor DNA (ctDNA). This can be detected through liquid biopsy in breast milk.
A purple gloved hand holds two blood test tubes.

New RNA Liquid Biopsy Platform Improves Cancer Detection

A new liquid biopsy platform has been developed that uses RNA "dark matter" to diagnose cancer types including pancreatic, lung and esophageal, in the early stages.
Illustration of DNA double helices on a yellow and pink polka dot background.

Oncology Researchers: Are You Getting the Most From Your Digital PCR Data?

This article discusses what good dPCR data looks like, how substandard equipment can detract from data quality and what oncology researchers can do to get high-quality dPCR data that will provide accurate and efficient insight into tumor load.
Floating cells with transparent membranes.
Industry Insight

Unlocking the “Morpholome” With AI-Powered Imaging

Technology Networks had the pleasure of speaking with Dr. Maddison Masaeli, co-founder and chief executive officer at Deepcell to learn about the REM-I platform, a single-cell analysis tool that utilizes AI-powered imaging to magnify insights into a cell’s phenotype and function.
Computer-generated image the gut and gut microbes.

Bacteria Detect DNA Shed by Colon Cancer Tumors in Mice

Engineered bacteria can detect tumor DNA shed by colon cancers into the gastrointestinal (GI) tract in mice, creating the potential for their use as biosensors to detect and respond to disease.